依照2000 Infusion Nursing Standards of Practice, 如果靜脈藥物過酸或過鹼，pH小於5或大於9，則需要以中央靜脈導管來作輸液，以避免血管傷害。

藥物酸鹼值 pH value

Vancomycin
Ciprofloxacin
Doxycycline
Epinephrine
Propranolol
Dopamine
Dobutamine
Midazolam
Nicardipine
Vinblastine
Cisplatin
Labetalol
Isoproterenol
Potassium
Amikacin
Gentamicin
Cefazolin
Ceftriaxone
5-FU 
Acycloivir
Ampicillin
Acetazolamide
Esomeprazole
Ganciclovior
Omeprazol
Phenytoin
Bactrim

2.4
3.3-4.6
1.8-3.3
2.2-5
2-4
2.5-5
2.5-5.5
2.9-3.7
3.5
3.5-5
3.5-4.5
3-4
2.5-4.5
4
4.5 (3.5-5.5)
3-5.5
4.5-6
6.6
9.2
10.5-11.6
8-10
9.2-9.6
9-10
9-11
11
12
10